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Winter 2014

Proto winter 2014 cover


The Problem of Replication

It’s disappointing when seemingly groundbreaking studies can’t be repeated. But it’s happening a lot.

No Easy Answers

The name—ductal carcinoma in situ—begs the question: how to treat a small breast lesion that has yet to spread.

Tangled Up In Tau

Trouble with the protein may underlie most kinds of dementia, perhaps including Alzheimer’s. New drugs could help.

A Tough Job Made Tougher

“Disabled” doctors? They don’t like the term or the implication, and their careers have been anything but limited.

Comprehension Test

For patients to be effective partners in their own care requires a basic grasp of medical terms that, shockingly, many don’t have.

A Call for Replication

Peter L. Slavin and David F. Torchiana on the value of reproducing research.

Bubble Power

Aiming tiny bursting bubbles at tumors could pave the way for new treatments.

Carolyn Greene: The Data Miner

Epidemiologist Carolyn Greene aims to use electronic health records to track chronic disease trends.

The Legacy of Agent Orange

The health effects of Agent Orange—used extensively during the Vietnam War—continue to be felt.

A New Epidemic Model

SARS revealed the existence of “super-spreaders,” who can infect dozens of people. The same, it appears, goes for other infectious diseases.

Doctress of Medicine

One hundred and fifty years ago, Rebecca Lee Crumpler became the first black woman to receive a medical degree in the United States.

In Framingham, Deep Cuts

Having run for more than 50 years, the Framingham Heart Study is in jeopardy because of deep budget cuts.

Go Live

In this short story, an IT guy reveals the human angle of dealing with new health care technology.

Defined: Helium Cliff

An impending helium shortage could greatly raise the price of helium, an element used to chill MRI scanners.

Does This Gene Look Patentable?

A Supreme Court ruling on whether genes can be patented didn’t give crystal clear answers.

When It’s All in Their Heads

Three physician bloggers discuss how to treat patients with imagined ailments.

A Second Life for Lungs

“Lung washing” is keeping donated lungs alive longer.

These Hands

At her great-uncle’s bedside, the author considers the genetic disorder that binds her family.

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