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Hed-inthelab Innovations in Basic Research

Q: How has talking to veterinarians changed you as a physician?

A: I recall a chimpanzee I consulted on with a severe form of heart failure... The basic medical approach was very similar to human medicine’s, but deeply informed by the patient’s ability to enjoy life and by consideration of patient suffering. I have come to believe that some of the most humanistic medicine today is actually being practiced by doctors whose patients are not human.

“We still don’t know what these lncRNAs are doing or how they work,” Rinn says. “We just know that if we take them away, bad things happen.”

An Avoidable Dementia

One tauopathy is entirely man-made, caused by concussions and other types of brain trauma.

From One Protein, Many Diseases

Depending on where tau tangles form in the brain, any of a number of types of dementia may occur.

Painting of a test tube

The Problem of Replication

It’s disappointing when seemingly groundbreaking studies can’t be repeated. But it’s happening a lot.

Popping bubble

Bubble Power

Aiming tiny bursting bubbles at tumors could pave the way for new treatments.


A Call for Replication

Peter L. Slavin and David F. Torchiana on the value of reproducing research.


A Second Act for Phages

As resistance to antibiotics grows, might phage therapy, a treatment that fell out of favor decades ago, be the answer?

cutting edge

A new system aims to detect malware that can infect hospitals' internal networks and even life-saving or-sustaining devices.

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community paramedicine [kə-myü-nə-tē ˌper-ə-ˈme-də-sən] n: a trend that repurposes emergency medical services to provide in-home chronic disease management and follow-up care

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